
Ultimate Vayne Guide: Video Tutorials & Pro Tips
League of Legends Vayne Champion Guide
Vayne is a late-game hypercarry marksman who excels at single-target damage and dueling. Here's everything you need to master this champion.

Vayne champion guide for League
Core Strategy Tips:
- Focus on safe farming during early game
- Aim to proc W passive with three consecutive auto-attacks
- Save Q (Tumble) for defensive positioning in teamfights
- Scale into mid and late game for maximum effectiveness
Strong Against:
- Mel (60.5% WR)
- Kai'Sa (54.4% WR)
- Ezreal (54.2% WR)
- Ziggs (54.1% WR)
- Sivir (53.9% WR)
- Smolder (53.5% WR)
Weak Against:
- Nilah (45.8% WR)
- Aphelios (49.4% WR)
- Lucian (49.7% WR)
- Caitlyn (49.7% WR)
- Varus (49.7% WR)
- Twitch (49.8% WR)
Best Support Synergies:
- Zyra (57.9% WR)
- Soraka (56.3% WR)
- Milio (55.4% WR)
- Leona (55.3% WR)
- Zilean (55.1% WR)
- Seraphine (54.5% WR)
Pro Tips for Success:
- Focus on farming safely early game
- Position carefully in teamfights
- Use W passive for favorable trades
- Maintain safe distance from threats
- Scale into late game for maximum impact
Key Mechanics:
- Master three-hit W proc combinations
- Use Q for repositioning and dodging
- Save E for self-peel against divers
- Time your ultimate for crucial fights
Remember to join Vayne communities to discuss strategies and stay updated with the latest builds and techniques.