Best Pyke Mid Runes & Winrates - Patch 15.4 Guide
Pyke Mid Runes & Matchups Guide
The optimal rune setup for Pyke Mid in patch 15.4 features Domination primary with Resolve secondary, achieving a 45.8% win rate across 384 matches.
Primary Runes (Domination):
- Keystone: Hail of Blades
- Sudden Impact
- Sixth Sense
- Ultimate Hunter
Secondary Runes (Resolve):
- Demolish
- Bone Plating
Key Matchups:
Unfavorable Matchups:
- Elise (43.2% WR)
- Taric (43.7% WR)
- Maokai (44.8% WR)
- Thresh (45.3% WR)
- Fiddlesticks (45.7% WR)
- Lulu (46.9% WR)
Favorable Matchups:
- Mel (53.9% WR)
- Senna (53.2% WR)
- Karma (52.2% WR)
- LeBlanc (52.0% WR)
- Leona (51.6% WR)
- Zoe (51.0% WR)
Best Duo Synergies:
- Ziggs (56.2% WR)
- Draven (53.2% WR)
- Jinx (51.3% WR)
- Miss Fortune (51.1% WR)
- Twitch (51.1% WR)
- Vayne (50.9% WR)
Essential Tips:
- Push and roam when Ultimate (R) is available
- Track enemy Flash cooldowns before using Ultimate
- Execute flanking maneuvers with Q during team fights
- Focus on side lane assistance after getting core items
These strategies maximize Pyke's mid-lane potential while leveraging his roaming and assassination capabilities.
