Precision and Domination runes provide Nilah optimal performance with a 52.5% win rate and 40.9% pick rate across 5,874 matches in patch 15.4.

Best Rune Setup:

• Primary (Precision): Conqueror, Triumph, Legend: Alacrity, Last Stand
• Secondary (Domination): Sudden Impact, Treasure Hunter

Strong Matchups:

• Twitch (58.6% WR)
• Ezreal (57.0% WR)
• Kai'Sa (57.0% WR)
• Samira (56.6% WR)
• Aphelios (55.8% WR)
• Ashe (55.2% WR)

Weak Against:

• Kog'Maw (44.8% WR)
• Xayah (46.0% WR)
• Hwei (48.0% WR)
• Smolder (48.2% WR)
• Sivir (49.5% WR)
• Jinx (49.6% WR)

Best Support Synergies:

• Taric (59.5% WR)
• Senna (57.6% WR)
• Karma (57.3% WR)
• Alistar (56.6% WR)
• Thresh (56.4% WR)
• Blitzcrank (56.3% WR)

Key Tips:

1. Maintain two E stacks for escape options during aggressive plays
2. Leverage early level 6 power spike with aggressive supports
3. Position for grouped fights to maximize E and R combo potential

For optimal play, consider using E aggressively when team fights occur in tight spaces, following up with R to maximize area damage. Your passive gives you an early level advantage, which creates strong all-in opportunities with your support at level 6.

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