Yasuo Mid Runes Guide: Best Patch 15.6 Setup with 50.2% Win Rate
Yasuo Mid Lane Runes Guide
Lethal Tempo is currently the optimal keystone for Yasuo in patch 15.6, maintaining a 50.2% win rate with a 75.4% pick rate across 2,248 matches.
Primary Runes (Precision)
- Lethal Tempo
- Triumph
- Legend: Alacrity
- Cut Down
Secondary Runes (Resolve)
- Bone Plating
- Overgrowth
Strong Matchups
- Tristana (73.3% WR)
- Swain (64.7% WR)
- Talon (63.9% WR)
- Fizz (62.2% WR)
- Jayce (61.9% WR)
- Sylas (60.6% WR)
Weak Matchups
- Kayle (31.3% WR)
- Annie (33.3% WR)
- Renekton (35.7% WR)
- Taliyah (36.5% WR)
- Galio (37.9% WR)
- Azir (38.9% WR)
Best Duo Synergies
- Diana (51.5% WR)
- Lee Sin (50.5% WR)
Essential Tips
- Use E through minion waves strategically, always leaving one minion as an escape route
- Time your ultimate carefully - don't engage on every knock-up, especially in unfavorable situations
- Conserve Windwall (W) for crucial moments, particularly against ganks or global ultimates
Champion Combos Master Yasuo's mechanics by learning his essential combo patterns and practicing them consistently.