
Twitch Champion Guide - Complete Build & Strategy | Patch 14.16.1
The Twitch is a unique assassin marksman known for his stealth and poison-based abilities that excel in the bot lane position.
Abilities Overview:
- Passive (Deadly Venom): Basic attacks apply poison stacks that deal percentage damage over 6 seconds, stacking up to 6 times
- Q (Ambush): Grants 10-14 seconds of camouflage followed by 30-50% attack speed
- W (Contaminate): Throws poison barrel that applies passive stacks and slows enemies by 25-45%
- E (Contaminate): Deals damage to nearby poisoned enemies based on accumulated stacks
- R (Spray and Pray): Grants 20-40 AD and 300 range for 6 seconds, with attacks piercing through enemies

Man in black shirt headshot
Optimal Skill Order:
- Start with Q (Ambush) at level 1
- Take E (Contaminate) at level 2
- Max priority: R > E > Q > W
Alternative Start:
- Against difficult matchups, start W with Doran's Ring
- Take E at level 2
- Use abilities to safely farm from distance
Core Build Path:
- Starting items focus on AD and sustain
- Build core items prioritizing:
- Attack Damage
- Attack Speed
- Critical Strike
- Later: Armor Penetration and Lifesteal
Gameplay Tips:
- Use Q strategically to position for surprise attacks
- Stack passive before using E for maximum damage
- Utilize ultimate in teamfights for multi-target damage
- Position carefully to maximize pierce damage with ultimate
- Reset Q cooldown by securing kills on poisoned targets
Strategic Advantages:
- Exceptional teamfight presence with ultimate
- Strong assassination potential through stealth
- Effective at both short and long-range combat
- Scales well into late game
- Can create chaos through unexpected positioning