Press the Attack is the optimal keystone rune for Support Pantheon, maintaining a 50.2% win rate in patch 15.4 across 11,071 matches, with a 51.4% pick rate.

Primary Runes (Precision)

• Press the Attack
• Triumph
• Legend: Alacrity
• Coup de Grace

Secondary Runes (Domination)

• Sudden Impact
• Relentless Hunter

Strong Matchups

• Sejuani (54.2% WR)
• Karthus (53.6% WR)
• Evelynn (52.6% WR)
• Zyra (51.5% WR)
• Zed (51.4% WR)

Weak Matchups

• Gwen (42.9% WR)
• Rek'Sai (44.1% WR)
• Darius (44.7% WR)
• Bel'Veth (45.4% WR)
• Rammus (45.9% WR)

Best Synergies

• Swain (56.8% WR)
• Ryze (56.0% WR)
• Cho'Gath (55.2% WR)
• Akali (54.9% WR)
• Cassiopeia (54.9% WR)

Key Tips:

• Utilize your Ultimate (R) for map-wide roaming and lane assistance
• Maintain early game presence to ensure effective E engagement opportunities
• Use Q for consistent poke damage while managing mana efficiency
• Coordinate ganks with your jungler to maximize kill potential
• Focus on objective control and vision around key areas

Remember to adapt your playstyle based on matchups and team composition, prioritizing roaming opportunities to impact other lanes while maintaining lane presence.

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