Neeko Mid Lane Runes Guide (Season 14)

The optimal rune setup for Neeko mid lane features Sorcery as primary and Inspiration as secondary, maintaining a 52.3% win rate across 7,813 matches in patch 14.24.

Primary Runes (Sorcery):

• Keystone: Arcane Comet
• Manaflow Band
• Transcendence
• Scorch

Secondary Runes (Inspiration):

• Biscuit Delivery
• Cosmic Insight

Strong Matchups:

• Zoe (55.9% WR)
• Swain (54.7% WR)
• Alistar (54.4% WR)
• Blitzcrank (53.3% WR)
• Brand (53.0% WR)

Weak Matchups:

• Poppy (46.6% WR)
• Janna (46.8% WR)
• Zyra (47.2% WR)
• Sona (47.4% WR)
• LeBlanc (48.1% WR)

Best ADC Synergies:

• Nilah (59.2% WR)
• Kog'Maw (54.5% WR)
• Miss Fortune (53.9% WR)
• Seraphine (53.5% WR)
• Samira (53.0% WR)

Essential Tips:

1. Only transform when enemies haven't spotted you
2. Use W speed boost for better Ultimate positioning
3. Maximize E root duration by hitting multiple minions before champions

Combat Combos:

• Basic Harass: E (root) > Q > Auto Attack
• All-in: E > Q > R > W (reposition)
• Chase/Escape: W (speed) > E (through minions) > Q

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