
Nautilus Support Best Runes & Matchups Patch 15.4
Nautilus Support Runes Guide
Optimal Rune Setup (Patch 15.4):
- Primary Tree: Resolve
- Secondary Tree: Inspiration
- Current Win Rate: 48.9%
- Pick Rate: 65.1% (based on 29,779 matches)
Best Primary Runes (Resolve):
- Keystone: Aftershock
- Shield Bash
- Second Wind
- Overgrowth
Best Secondary Runes (Inspiration):
- Hextech Flashtraption
- Biscuit Delivery
Strong Against:
- Yuumi (54.5% WR)
- Mel (53.5% WR)
- Zilean (53.2% WR)
- LeBlanc (52.8% WR)
- Elise (52.5% WR)
- Pantheon (52.5% WR)
Weak Against:
- Taric (36.7% WR)
- Renata Glasc (42.7% WR)
- Rell (43.3% WR)
- Tahm Kench (43.9% WR)
- Bard (45.0% WR)
- Neeko (45.3% WR)
Best ADC Synergies:
- Samira (52.1% WR)
- Yasuo (51.4% WR)
- Sivir (51.2% WR)
- Kog'Maw (50.9% WR)
- Nilah (50.8% WR)
- Xayah (50.7% WR)
Pro Tips:
- Save your Q (hook) until enemies use their escape abilities or misposition
- Use Q to catch overextended enemies during tower sieges
- Utilize your strong CC for roaming opportunities after recalls
Essential Combos:
- Available in-game through the combos menu
For optimal performance, coordinate engages with your ADC and time your roams to support other lanes when possible.