Lissandra Mid is currently sitting at a 52.0% win rate based on 5,515 matches. Here's the optimal build and strategy guide:

Core Build:

• First Item: Malignance
• Boots: Sorcerer's Shoes
• Core Items: Shadowflame, Zhonya's Hourglass, Rabadon's Deathcap, Void Staff

Runes:

• Primary: Electrocute, Cheap Shot, Grisly Mementos, Ultimate Hunter
• Secondary: Manaflow Band, Transcendence
• Shards: Adaptive Force (x2), Health Scaling

Summoner Spells:

• Flash
• Teleport

Skill Order: Q > W > E

Strong Matchups (55%+ WR):

• Karma (58.4%)
• Mel (56.1%)
• Aurora (54.8%)
• Kayle (54.1%)
• Galio (54.0%)

Weak Matchups (Sub 46% WR):

• Swain (43.1%)
• Anivia (43.9%)
• Taliyah (44.7%)
• Annie (45.2%)
• Vel'Koz (45.6%)

Key Tips:

• Line up Q to hit both minions and enemy champion when pushing
• Use E for flanking engages, ensuring team can follow up
• When behind, use abilities to peel for ADC
• Can use ultimate (R) on enemy frontline to protect carries

Best Synergies:

• Shyvana (56.7%)
• Master Yi (56.1%)
• Bel'Veth (54.8%)
• Briar (53.9%)
• Kindred (53.5%)

Alternative Build Options:

• Luden's Companion first item (52.1% WR)
• Arcane Comet rune setup with Blackfire Torch first item (52.5% WR)

Adjust your item builds and rune choices based on specific matchups and team compositions.

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