Heimerdinger's optimal runes for Bot lane feature Sorcery/Precision, boasting a 59.0% win rate with a 35.3% pick rate across 446 matches.

Primary Runes (Sorcery):

• Arcane Comet (Keystone)
• Axiom Arcanist
• Transcendence
• Gathering Storm

Secondary Runes (Precision):

• Presence of Mind
• Legend: Haste

Strong Against:

• Trundle (62.5% WR)
• Shen (62.3% WR)
• Volibear (60.7% WR)
• Pantheon (60.3% WR)
• Mordekaiser (59.1% WR)
• Warwick (58.5% WR)

Weak Against:

• Akali (39.8% WR)
• Kled (40.9% WR)
• Yasuo (42.3% WR)
• Ornn (43.6% WR)
• Aurora (44.6% WR)
• Zed (45.3% WR)

Best Duo Synergies:

• Master Yi (57.0% WR)
• Hecarim (56.9% WR)
• Kindred (56.8% WR)
• Xin Zhao (56.3% WR)
• Darius (56.2% WR)
• Wukong (55.2% WR)

Essential Tips:

1. Place Turrets (Q) before laning phase begins to conserve mana and secure early push advantage
2. Always fight within Turret (Q) range to maximize damage output
3. Cast bomb (E) slightly behind enemies while in Turret range for optimal stun probability and damage

These strategies are particularly effective in patch 15.5, helping secure Heimerdinger's strong position in the current meta.

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