Galio Mid Runes & Matchups Guide [Patch 15.4]

Current Best Rune Setup: Resolve (Primary) / Sorcery (Secondary)

• Win Rate: 49.8%
• Pick Rate: 48.2%
• Sample Size: 34,736 matches

Primary Runes (Resolve):

• Keystone: Aftershock
• Demolish
• Second Wind
• Overgrowth

Secondary Runes (Sorcery):

• Manaflow Band
• Transcendence

Strong Matchups:

• Diana (55.6% WR)
• Katarina (54.6% WR)
• Mel (54.3% WR)
• Malzahar (54.1% WR)
• Akali (53.5% WR)
• Sylas (53.2% WR)

Weak Matchups:

• Swain (43.0% WR)
• Anivia (46.1% WR)
• Veigar (46.4% WR)
• Ahri (46.5% WR)
• Karma (46.7% WR)
• Ambessa (46.8% WR)

Best Jungle Synergies:

• Amumu (55.5% WR)
• Bel'Veth (53.8% WR)
• Warwick (53.2% WR)
• Gwen (53.1% WR)
• Darius (53.1% WR)
• Udyr (52.9% WR)

Essential Tips:

1. Post-level 6: Play conservatively as your ultimate (R) provides utility rather than direct combat power
2. Wave Management: Keep the wave close to your tower to set up jungle ganks
3. Roaming Strategy: Before using R to roam, clear waves quickly using Q + E + empowered auto-attack

This data is based on high-elo matches in the current patch (15.4).

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