Based on 53 matches in patch 15.4, Elise Mid achieves a 50.9% win rate with a 27.0% pick rate using the Domination/Precision rune combination.

Primary Runes (Domination)

• Keystone: Electrocute
• Sudden Impact
• Deep Ward
• Relentless Hunter

Secondary Runes (Precision)

• Triumph
• Coup de Grace

Strong Against:

• Zoe (61.1% WR)
• Swain (60.4% WR)
• Brand (60.4% WR)
• Tahm Kench (59.3% WR)
• Shaco (59.1% WR)
• Ashe (58.3% WR)

Weak Against:

• Taric (36.5% WR)
• Sona (42.1% WR)
• Maokai (45.7% WR)
• Renata Glasc (47.0% WR)
• Braum (47.1% WR)
• Seraphine (47.7% WR)

Best Duo Synergies:

• Aphelios (56.1% WR)
• Ashe (55.7% WR)
• Samira (52.2% WR)
• Twitch (52.1% WR)
• Ezreal (52.1% WR)
• Jinx (52.0% WR)

These statistics are based on current patch data and provide a comprehensive overview of Elise's performance in the mid lane role.

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