Twitch Bot Lane Runes Guide

Lethal Tempo is currently the optimal keystone for Twitch, boasting a 50.9% win rate in Patch 14.24 with a 46.9% pick rate (based on 42,521 matches).

Primary Runes (Precision)

• Lethal Tempo (Keystone)
• Presence of Mind
• Legend: Alacrity
• Cut Down

Secondary Runes (Domination)

• Sudden Impact
• Ultimate Hunter

Counter Matchups Weak Against:

• Nilah (41.8% WR)
• Corki (46.6% WR)
• Hwei (46.8% WR)
• Tristana (47.1% WR)
• Seraphine (47.1% WR)
• Brand (47.2% WR)

Strong Against:

• Smolder (53.0% WR)
• Aphelios (52.9% WR)
• Zeri (51.8% WR)
• Jinx (51.7% WR)
• Sivir (51.6% WR)
• Jhin (51.4% WR)

Best Support Synergies

• Camille (55.9% WR)
• Sylas (55.0% WR)
• Taric (54.7% WR)
• Braum (53.4% WR)
• Shen (52.9% WR)
• Elise (52.7% WR)

Key Tips

1. Position your Ultimate (R) to hit multiple enemies for maximum damage output
2. Play defensively in the early game until your first item power spike
3. Prioritize extended trades to maximize your passive poison damage

Champion Difficulty: Hard

This build and guide is optimized for Bot Lane Twitch in the current meta, focusing on maximizing damage output while maintaining survivability through proper positioning and timing.

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