Best Runes for Orianna Mid Lane | Patch 15.3 Guide

Best Runes for Orianna Mid Lane | Patch 15.3 Guide

By Marcus Chen

February 12, 2025 at 07:38 AM

Orianna's Optimal Rune Setup

Sorcery + Precision runes provide Orianna with the best performance in mid lane, maintaining a 50.0% win rate across 12,260 matches in patch 15.3.

Primary Runes (Sorcery):

  • Keystone: Summon Aery
  • Manaflow Band
  • Transcendence
  • Gathering Storm

Secondary Runes (Precision):

  • Presence of Mind
  • Legend: Haste

Strong Matchups:

  • Corki (57.7% WR)
  • Smolder (57.7% WR)
  • Jayce (56.1% WR)
  • Karma (54.8% WR)
  • Naafiri (54.7% WR)
  • Fizz (54.2% WR)

Challenging Matchups:

  • Cho'Gath (42.9% WR)
  • Kayle (43.2% WR)
  • Qiyana (43.7% WR)
  • Taliyah (44.3% WR)
  • Veigar (44.5% WR)
  • Swain (45.4% WR)

Best Synergizing Junglers:

  • Master Yi (53.1% WR)
  • Nocturne (53.0% WR)
  • Rek'Sai (52.9% WR)
  • Zyra (52.4% WR)
  • Amumu (52.2% WR)
  • Hecarim (51.9% WR)

Key Tips:

  1. Use poke combos to harass but remain cautious of ganks
  2. Position in backline during teamfights, keeping your ball on engaging allies
  3. Focus on safe farming and coordinated plays, as Orianna lacks survivability compared to other mid laners

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