Mel Mid Runes Guide (Patch 15.4)

The optimal rune setup for Mel in mid lane combines Sorcery (primary) and Precision (secondary), achieving a 45.7% win rate across 80,451 matches.

Primary Runes (Sorcery):

• Keystone: Arcane Comet
• Manaflow Band
• Transcendence
• Gathering Storm

Secondary Runes (Precision):

• Presence of Mind
• Legend: Haste

Best Matchups:

• Naafiri (52.1% WR)
• Swain (51.2% WR)
• Yone (50.3% WR)
• Vex (49.5% WR)
• Twisted Fate (48.6% WR)
• Lux (48.6% WR)

Challenging Matchups:

• Kassadin (40.3% WR)
• Annie (40.8% WR)
• Kayle (40.9% WR)
• Fizz (41.0% WR)
• Cassiopeia (41.0% WR)
• Aurelion Sol (41.5% WR)

Best Duo Synergies:

• Darius (50.6% WR)
• Teemo (50.0% WR)
• Qiyana (49.2% WR)
• Trundle (49.2% WR)
• Gwen (49.1% WR)
• Nocturne (48.8% WR)

Essential Tips:

1. Prioritize using your Passive and bonus damage on enemy champions over minions to establish lane dominance
2. Reserve W as your defensive ability - avoid using it unnecessarily and play cautiously when it's on cooldown
3. Maximize efficiency by positioning Q and E to simultaneously push the lane and harass your opponent

Remember to check professional builds and match-specific adjustments based on team compositions and matchups.

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