Elise Support Runes Guide

Optimal Rune Setup:

• Primary: Domination
• Secondary: Precision
• Win Rate: 51.8%
• Pick Rate: 64.8%
• Based on 29,979 matches

Primary Path (Domination):

• Keystone: Electrocute
• Sudden Impact
• Deep Ward
• Relentless Hunter

Secondary Path (Precision):

• Triumph
• Coup de Grace

Strong Matchups:

• LeBlanc (58.7%)
• Mel (58.4%)
• Sylas (57.3%)
• Pyke (56.6%)
• Swain (55.1%)
• Brand (55.0%)

Weak Matchups:

• Taric (43.1%)
• Neeko (45.7%)
• Sona (46.6%)
• Maokai (47.0%)
• Braum (48.0%)
• Renata Glasc (48.4%)

Best ADC Synergies:

• Kog'Maw (57.1%)
• Ziggs (56.7%)
• Ashe (54.7%)
• Draven (53.6%)
• Miss Fortune (53.4%)
• Sivir (52.4%)

This setup maximizes Elise's early game pressure and roaming potential while maintaining strong kill threat in lane. Electrocute provides burst damage for trades, while Precision secondary runes enhance survivability and damage output in extended fights.

For detailed combos, champion mastery tips, and pro builds, check specialized Elise communities and resources. These runes are particularly effective in patch 15.4, but may need adjustment based on future balance changes.

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