Precision / Resolve combination achieves a 51.1% win rate with 64.4% pick rate across 8,908 matches for Akshan mid in patch 15.3.

Best Runes Setup Primary (Precision):

• Press the Attack (Keystone)
• Presence of Mind
• Legend: Alacrity
• Coup de Grace

Secondary (Resolve):

• Shield Bash
• Bone Plating

Strong Against:

• Smolder (60.3%)
• Yone (58.7%)
• Karma (58.6%)
• Zed (58.2%)
• Qiyana (58.1%)
• Aurora (57.9%)

Weak Against:

• Naafiri (42.7%)
• Irelia (44.1%)
• Diana (45.6%)
• Anivia (45.8%)
• Lissandra (46.0%)
• Vex (46.0%)

Best Jungle Synergies:

• Karthus (57.0%)
• Hecarim (56.6%)
• Udyr (55.9%)
• Xin Zhao (54.6%)
• Gwen (54.1%)
• Amumu (54.0%)

Essential Tips:

1. Conserve your E ability during laning phase to avoid vulnerability to all-ins
2. Auto-attack before Q to stack passive procs efficiently
3. Time Ultimate usage when enemy CC abilities are on cooldown to avoid interruption

Optimal Combo Sequence: Auto-attack > Q > Auto-attack (maximizes passive proc potential and damage output)

This setup provides optimal performance for Akshan in the mid lane, focusing on early game presence and scaling potential through precision runes while maintaining survivability with resolve secondary runes.

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